Radchem cc po box 166982 brackendowns alberton 1454 telephone. Pph cerkamed material safety data sheet methylene chloride. Vwr international llc radnor corporate center building one. Methylene chloride dichloromethane related niosh resources. With these larger bottles attached your synthesizer can produce up to 40 average primerlength oligonucleotides with no bottle changes, reducing a. Dichloromethane dcm or methylene chloride is an organochloride compound with the formula c h 2 cl 2. Original on 05222017 page 1 of 6 safety data sheet dichloromethane hplc 1. Dichloromethane is a member of the class of chloromethanes that is methane in which two of the hydrogens have been replaced by chlorine. Inhalation of high concentrations may cause central nervous system effects. With these larger bottles attached your synthesizer can produce up to 40 average primerlength oligonucleotides with no. This colorless, volatile liquid with a moderately sweet aroma is widely used as a solvent. Dichloromethane technical data sheet and specification. A dense, nonflammible colourless liquid at room temperature b. Accidental release measures personal precautions, protective equipment and emergency procedures.
Dichloromethane can also be absorbed into the body via inhalation, ingestion or skin contact. Extinguishing media suitable extinguishing media use water spray, alcoholresistant foam, dry chemical or carbon dioxide. It is a colourless liquid with penetrating etherlike or mild sweet odour. Understanding the potential hazards of dichloromethane.
This hplc grade dichloromethane comes in a convenient large volume for abi 394 nucleic acid synthesizers, resulting in extended handsfree dna synthesis. The study must reproduce the accident or injection and exposure to dichloromethane with an analysis of the damage to the tissues and a medical evaluation of the consequences. Methylene chloride is metabolically converted to carbon monoxide after systemic absorption, which yields increased concentrations of carboxyhemoglobin in the blood. Dichloromethane is a clear, colourless, volatile liquid with a sweet odour. Worksafe australia categorises dichloromethane into category 3, a suspected human carcinogen. Dichloromethane technical data sheet and specification 8000151. July 3, 2007 the dow chemical company page 4 of 7 epidemiological studies on more than 6,000 people exposed to methylene chloride in their workplace using over 35 years of observations showed no increase in deaths from cancer or any other disease. However, we make no warranty of merchantibility or any other warranty, express or implied, wi th respect to such information, and we assum e no liability resulting from its use. Dichloromethane is used as an aerosol solvent, in the production of pharmaceuticals and as a degreasing agent in electronics and manufacturing industries. Can cause gastrointestinal irritation, nausea, vomiting, and diarrhea.
The information provided on this safety data sheet is correct to the best of our knowledge, information and belief at the date of its. Dichloromethane page 8 of 14 incident management health effects major route of exposure dichloromethane has direct solvent toxicity and may be toxic due to its carbon monoxide, formaldehyde, formic acid and carbon dioxide metabolites inhalation is. We continually provide comprehensive safety and regulatory data on our safety data sheets promoting safe usage and handling of our products. Dichloromethane can affect the body if it is inhaled or swallowed, or if it comes in contact with the eyes or skin. En section 1 identification of the substance mixture and of the company undertaking product identifier product name dichloromethane chemical name methylene chloride. Chemical product and company identification product name. Dichloromethane 75 09 2 100 50 ppm 25 ppm 125 ppm section iii hazard identification routes of exposure. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database.
Safety data sheet northwest missouri state university. Material safety data sheet methylene chloride msds section 1. Regulatory information tsca inventory status all ingredients are listed on the tsca inventory. Safety data sheet dichloromethane bdh11 page 1 16 version 1. A recent case of a dichloromethane injection injury. Dichloromethane has been restricted since 1976 and it is currently restricted in annex iii entry 7 of the cosmetics directive 76768eec to a. Dichloromethane can be synthesised by the reaction between chlorine gas and methane or chloromethane at high.
Sds of dichloromethane, safety data sheets, cas 75092. Please ensure that this msds is given to, and explained to people using this product. Industrial, manufacturing or laboratory use manufacturer. Dichloromethane page 4 of 14 incident management physicochemical properties cas number 75092 molecular weight 84. Very hazardous in case of eye contact irritant, of. In severe cases kidney damage, fitting, heart problems and coma can occur. Dichloromethane buy dichloromethane reagent chemicals. Extinguishing media which must not be used for safety reasons do not use water jet. Hazard identification very hazardous in case of eye contact irritant, of ingestion, of inhalation. Material safety data sheet dichloromethane educational innovations. Further action will be the responsibility of the medical specialist. The international agency for research on cancer classifies dichloromethane as a possible human carcinogen.
July 3, 2007 the dow chemical company page 4 of 7 epidemiological studies on more than 6,000 people exposed to methylene chloride in their workplace using over 35 years of observations showed no. Material safety data sheet section 1 dichloromethane 1 chemical product and company identification msds name. Other common names for dichloromethane are methylene chloride and dcm. Product identification name methylene chloride synonyms dichloromethane.
Sigmaaldrich 3050 spruce street saint louis mo 63103 usa telephone. Other information revision b, june 2015 the information contained herein is provided in good faith and is believed to be correct as of the date hereof. Although it is not miscible with water, it is polar, and miscible with many organic solvents. Identification of the substancemixture and of the companyundertaking 1. Product name dichloromethane chemical name methylene chloride proper shipping name dichloromethane chemical formula ch2cl2 other means of identification not available cas number 75092.
Symptoms include headache, lightheadedness, blurred vision, confusion, agitation and skin rashes. Dichloromethane exposure may cause the heart to beat irregularly or stop. It is moderately soluble in water 2 g100 ml at 20 c and soluble in most. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. This chemicalproduct is not and cannot be distributed in commerce as defined in tsca section 35 or processed as defined in tsca section 3 for consumer paint or coating removal. Dichloromethane page 8 of 14 incident management health effects major route of exposure dichloromethane has direct solvent toxicity and may be toxic due to its carbon monoxide, formaldehyde, formic acid and carbon dioxide metabolites inhalation is the most common cause of toxicity. Tenant notification fact sheet for dichloromethane is available in portable document format pdf, 15kb this fact sheet is provided to fulfill new york state department of health requirements for preparation of generic fact sheets under article 27 title 24, section 272405 of the environmental conservation law. Unfortunately, any new entry to the dichloromethane msds document would require a detailed study with animals to be performed by a speci. Despite this ubiquitous presence, the vast majority of all dichloromethane is the result of industrial synthesis.
Material safety data sheet methylene chloride dichloromethane page 1 of 6 msds is prepared in accordance with the regulation ec no 19072006 of the european parliament and of the council of 18 december 2006 concerning the registration, evaluation, authorization and restriction of chemicals reach, regulation ue no 4532010 of the european. However, we make no representation as to the comprehensiveness or accuracy of the info rmation. Material safety data sheet dichloromethane msds section 1. Long term exposures at high levels may damage the liver and brain. Other companies are charging thousands of dollars to set up. Dichloromethane can be found in nature, from volcanoes and wetlands, to algae and the ocean. Section i chemical product and company identification. Special hazards arising from the substance or mixture. Product identifier product name dichloromethane lrg product number 1203 synonyms.
Dichloromethane also commonly known as methylene chloride, methylene dichloride, diclo and dcm is a clear, slightly sweet smelling organic liquid chemical solvent which can be pose significant workplace safety risks if strict handling instructions are. Details of the supplier of the safety data sheet 2. Methylene chloride mc means an organic compound with chemical formula. Safety data sheet dichloromethane lrg according to regulation ec no 19072006, annex ii section 1. A member of the class of chloromethanes that is methane in which two of the hydrogens have been replaced by chlorine.
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